JIP2 Antibody


Western Blot: JIP2 Antibody [NBP1-31411] - Sample(30 ug whole cell lysate) A:Hep G2 7.5% SDS PAGE, antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: JIP2 Antibody [NBP1-31411] - Analysis of A431, using NBP1-31411 at 1:200 dilution.
Immunohistochemistry-Paraffin: JIP2 Antibody [NBP1-31411] - Paraffin-embedded lung SCC xenograft, using antibody at 1:100 dilution.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC

Order Details

JIP2 Antibody Summary

Recombinant protein encompassing a sequence within the center region of human JIP1. The exact sequence is proprietary.
Cytoplasm, Cytoplasm, perinuclear region, Nucleus
Immunogen affinity purified
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  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
0.01% Thimerosal
Immunogen affinity purified

Alternate Names for JIP2 Antibody

  • C-Jun-amino-terminal kinase-interacting protein 2
  • homologous to mouse JIP-1
  • IB-2
  • IB2JIP2Mitogen-activated protein kinase 8-interacting protein 2
  • islet-brain 2
  • islet-brain-2
  • JIP-2
  • JNK MAP kinase scaffold protein 2
  • JNK MAP kinase scaffold protein JIP2
  • JNK-interacting protein 2
  • mitogen-activated protein kinase 8 interacting protein 2
  • PRKM8 interacting protein-like


c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family. JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, Ser 63 and Ser 73, resulting in transcriptional activation. Two additional JNK family members have been identified as JNK2 and JNK3. JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, thereby inhibiting JNK-regulated gene expression. Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, which are targets of the JNK signaling pathway. JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain. ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding. Multiple splice variants of JIP-1, including JIP-1b, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, have been identified in brain.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Additional JIP2 Products

Array NBP1-31411

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Gene Symbol MAPK8IP2