Jagged 2 Antibody

Product Discontinued

Jagged 2 Antibody Summary

• Immunogen: Anti-Jagged 2 [RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 111-128 of Mouse Jagged 2. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1. Expected to cross-react with rat Jagged 2.
• Specificity: Expected to cross-react with rat Jagged-2. Jagged 2 is a Notch ligand, which shows distinct expression patterns in the developing and adult brain that overlaps that of Notch1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: JAG2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000-1:50000
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
• Preservative: 0.01% Sodium Azide
• Concentration: 0.9 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Jagged 2 Antibody

• HJ2
• JAG2
• Jagged 2
• Jagged2
• protein jagged-2
• SER2

Background

The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: JAG2
• Uniprot:
  • Q9QYE5()