ISCU Antibody (OTI4F5) [mFluor Violet 450 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI4F5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

ISCU Antibody (OTI4F5) [mFluor Violet 450 SE] Summary

• Immunogen: Full length human recombinant protein of human ISCU (NP_055116) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ISCU
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ISCU Antibody (OTI4F5) [mFluor Violet 450 SE]

• 2310020H20Rik
• HML
• hnifU
• iron-sulfur cluster assembly enzyme ISCU, mitochondrial
• iron-sulfur cluster scaffold homolog (E. coli)
• IscU iron-sulfur cluster scaffold homolog (E. coli)
• IscU iron-sulfur cluster scaffold homolog
• IscU
• ISU2
• MGC74517
• NIFU
• NifU-like N-terminal domain containing
• NifU-like N-terminal domain-containing protein
• NifU-like protein
• NIFUN

Background

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ISCU