IRE1 [p Ser724] Antibody (24GB5220)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF
• Clone: 24GB5220
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

IRE1 [p Ser724] Antibody (24GB5220) Summary

• Immunogen: A synthesized peptide derived from human Phospho-IRE1 (S724) (Uniprot: O75460)
• Modification: p Ser724
• Specificity: This antibody detects endogenous levels of ERN1 only when phosphorylated at S724
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: ERN1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for IRE1 [p Ser724] Antibody (24GB5220)

• EC 2.7.11
• endoplasmic reticulum to nucleus signaling 1
• Endoplasmic reticulum-to-nucleus signaling 1
• ER to nucleus signalling 1
• FLJ30999
• hIRE1p
• inositol-requiring 1
• Inositol-requiring protein 1
• IRE1a
• ire1-alpha
• IRE1MGC163279
• IRE1P
• MGC163277
• protein kinase/endoribonuclease
• serine/threonine-protein kinase/endoribonuclease IRE1

Background

IRE1 is encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. IRE1 possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ERN1