IRE1 Products

Description

IRE1 is encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. IRE1 possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

Bioinformatics

Product By Gene ID	2081
Alternate Names	EC 2.7.11 endoplasmic reticulum to nucleus signaling 1 Endoplasmic reticulum-to-nucleus signaling 1 ER to nucleus signalling 1 FLJ30999 hIRE1p inositol-requiring 1 Inositol-requiring protein 1 IRE1a ire1-alpha IRE1MGC163279 IRE1P MGC163277 protein kinase/endoribonuclease serine/threonine-protein kinase/endoribonuclease IRE1

Related IRE1 Blog Posts

Check out the latest blog posts on IRE1.

IRE1: Apoptosis, Autophagy and ER Stress Response IRE1 resides in the endoplasmic reticulum (ER) as a transmembrane protein with both serine-threonine kinase and endoribonuclease activities. It acts as an unfolded protein response (UPR) sensor through XBP1 transcriptional activation and has been foun...    Read more.

Read more IRE1 related blogs.