IP3KC Antibody

Western Blot: IP3KC Antibody [NBP1-36962] - taining of Human Pancreas (A), Heart (B) and Skeletal Muscle (C) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

IP3KC Antibody Summary

• Description: Novus Biologicals Goat IP3KC Antibody (NBP1-36962) is a polyclonal antibody validated for use in WB and ELISA. Anti-IP3KC Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-ETERPKQKTEPDRSS corresponding to internal region according to NP_079470.1.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ITPKC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1:100-1:2000
• Application Notes: WB: Approx. 75 kDa band observed in human pancreas lysates (calculated MW of 75.2 kDa band according to NP_079470.1).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for IP3KC Antibody

• inositol 14,5-trisphosphate 3-kinase CIP3K C
• inositol-trisphosphate 3-kinase C
• InsP 3 kinase C
• InsP 3-kinase C
• IP3 3-kinase C
• IP3-3KC
• IP3KCEC 2.7.1.127

Background

Inositol 1,4,5-trisphosphate 3-kinase (ITPK) catalyzes the phosphorylation of Ins(1,4,5)P3 to Ins(1,3,4,5)P4, both of which are modulators of calcium homeostasis. ITPK isoforms include ITPKA (MIM 147521), ITPKB (MIM 147522), and ITPKC, all of which contain a conserved catalytic unit in their C termini, but have unique N-terminal sequences and tissue distributions.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IP3KC Antibody (NBP1-36962)(1)

Publication using NBP1-36962

• Onouchi Y, Gunji T, Burns JC et al. ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. Nat Genet 2008-01-01 [PMID: 18084290]

Bioinformatics

• Gene Symbol: ITPKC
• Entrez:
  • 80271(Human)
• Uniprot:
  • NP_079470.1(Human)