Integrin beta 6 Antibody [Unconjugated]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Conjugate Size Price
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Catalog# & Formulation Size Price

Integrin beta 6 Antibody [Unconjugated] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin beta 6
Gly22-Asn706
Accession # Q9Z0T9
Specificity
Detects mouse Integrin beta 6 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ITGB6
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 5-15 ug/mL
  • Western Blot 0.1 ug/mL
Publications
Read Publications using
AF2389 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin beta 6 Antibody [Unconjugated]

  • Integrin beta 6
  • integrin beta-6
  • integrin, beta 6
  • ITGB6

Background

Integrin beta 6 is a type I transmembrane Integrin beta subunit that heterodimerizes with alpha V subunits in the epithelial restricted integrin alpha V/ beta 6. The extracellular domain of mouse Integrin beta 6 contains a collagen binding von-Willebrand factor A domain and multiple truncated EGF-like motifs. Mouse Integrin beta 6 extracellular domain shares 96% and 91% amino acid sequence identity with the corresponding regions of the rat and human protein, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Integrin beta 6 Antibody (AF2389)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC, IHC, Western Blot.


Filter By Application
ICC
(1)
IHC
(1)
Western Blot
(3)
All Applications
Filter By Species
Human
(1)
Mouse
(4)
All Species
Showing Publications 1 - 5 of 5.
Publications using AF2389 Applications Species
JA Pace, R Bronstein, Y Guo, Y Yang, CC Estrada, N Gujarati, DJ Salant, J Haley, AB Bialkowska, VW Yang, JC He, SK Mallipattu Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney Science Advances, 2021;7(36):eabg6600. 2021 [PMID: 34516901] (IHC, Mouse) IHC Mouse
T Xu, Z Lu, Z Xiao, F Liu, Y Chen, Z Wang, S Zhu, Y Song Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-?v&beta6 integrin in liver fibrosis Cell Death Dis, 2020;11(3):199. 2020 [PMID: 32251270] (ICC, Mouse) ICC Mouse
J Bi, L Koivisto, A Pang, M Li, G Jiang, S Aurora, Z Wang, GR Owen, J Dai, Y Shen, D Grenier, M Haapasalo, L Häkkinen, H Larjava Suppression of ?v?6 Integrin Expression by Polymicrobial Oral Biofilms in Gingival Epithelial Cells Sci Rep, 2017;7(1):4411. 2017 [PMID: 28667248] (Western Blot, Human) Western Blot Human
Mohazab L, Koivisto L, Jiang G, Kytomaki L, Haapasalo M, Owen G, Wiebe C, Xie Y, Heikinheimo K, Yoshida T, Smith C, Heino J, Hakkinen L, McKee M, Larjava H Critical role for alphavbeta6 integrin in enamel biomineralization. J Cell Sci, 2013;126(0):732-44. 2013 [PMID: 23264742] (Western Blot, Mouse) Western Blot Mouse
Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L45-56. 2010 [PMID: 19897741] (Western Blot, Mouse) Western Blot Mouse

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Bioinformatics

Gene Symbol ITGB6
Uniprot