Recombinant Human INCA His Protein

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SDS-Page: Recombinant Human INCA Protein [NBP2-22737]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human INCA His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-110 of Human INCA

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADKVLK EKRKQFIRSV GEGTINGLLG ELLETRVLSQ EEIEIVKCEN ATVMDKARAL LDSVIRKGAP ACQICITYIC EEDSHLAGTL GLSAGPTSGN HLTTQDSQIV LPS

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CARD17
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
14.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH 8.0), 0.15 M NaCl, 20% glycerol, 1 mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95%, by SDS-PAGE

Alternate Names for Recombinant Human INCA His Protein

  • caspase recruitment domain family, member 17
  • caspase recruitment domain-containing protein 17
  • Caspase-1 inhibitor INCA
  • INCAInhibitory CARD
  • inhibitory caspase recruitment domain (CARD) protein
  • Inhibitory caspase recruitment domain protein

Background

CARD17 is a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. This protein inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, CARD17 do not induce NF-kappa-B activation. Recombinant human CARD17 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for INCA Recombinant Protein (NBP2-22737) (0)

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Bioinformatics

Gene Symbol CARD17