Host: Rabbit Polyclonal
Applications: WB, ELISA
Host: Mouse Polyclonal
INCA, also known as CAR17 or Caspase recruitment domain-containing protein 17, is a 110 amino acid protein that is 12 kDa; cytoplasm located; regulates procaspase-1/CASP1 activation involved in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation; and acts as an inhibitor of the release of IL1B in response to LPS in monocytes. Current research is being pursued on this protein involvement in several diseases and disorders including cancer, familial mediterranean fever, shigellosis, cowpox, neurodegenerative disease, vascular disease, mevalonic aciduria, tularemia, dermatitis, lung disease, legionnaires' disease, and arthritis. This protein has been linked to the proteolysis and regulation of apoptotic process pathways where it interacts with CASP1, CARD16, and CARD18 proteins.
|Product By Gene ID
- Inhibitory caspase recruitment domain protein
- inhibitory caspase recruitment domain (CARD) protein
- Caspase-1 inhibitor INCA
- INCAInhibitory CARD
- caspase recruitment domain-containing protein 17
- caspase recruitment domain family, member 17
Research Areas for INCA
Find related products by research area and learn more about each of the different research areas below.Apoptosis
Bioinformatics Tool for INCA
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