INCA Products

INCA Antibody
INCA Antibody
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
INCA Antibody (1G6)
INCA Antibody (1G6)
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
INCA Antibody
INCA Antibody
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
INCA Overexpression Lysate (N ...
INCA Overexpression Lysate (Native)
Species: Hu
Applications: WB
Recombinant Human INCA Protei ...
Recombinant Human INCA Protein
Species: Hu
Applications: PAGE


INCA, also known as CAR17 or Caspase recruitment domain-containing protein 17, is a 110 amino acid protein that is 12 kDa; cytoplasm located; regulates procaspase-1/CASP1 activation involved in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation; and acts as an inhibitor of the release of IL1B in response to LPS in monocytes. Current research is being pursued on this protein involvement in several diseases and disorders including cancer, familial mediterranean fever, shigellosis, cowpox, neurodegenerative disease, vascular disease, mevalonic aciduria, tularemia, dermatitis, lung disease, legionnaires' disease, and arthritis. This protein has been linked to the proteolysis and regulation of apoptotic process pathways where it interacts with CASP1, CARD16, and CARD18 proteins.


Entrez Human
Uniprot Human
Product By Gene ID 440068
Alternate Names
  • Inhibitory caspase recruitment domain protein
  • inhibitory caspase recruitment domain (CARD) protein
  • Caspase-1 inhibitor INCA
  • INCAInhibitory CARD
  • caspase recruitment domain-containing protein 17
  • caspase recruitment domain family, member 17

Research Areas for INCA

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Bioinformatics Tool for INCA

Discover related pathways, diseases and genes to INCA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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