IMPDH1 Antibody (3G6) - Azide and BSA Free

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01] - IMPDH1 monoclonal antibody (M01), clone 3G6. Western Blot analysis of IMPDH1 expression in HeLa [L013V1].

Western Blot: IMPDH1 Antibody (3G6) [H00003614-M01] - IMPDH1 monoclonal antibody (M01), clone 3G6 Analysis of IMPDH1 expression in Hela S3 NE.

ELISA: IMPDH1 Antibody (3G6) [H00003614-M01] - Detection limit for recombinant GST tagged IMPDH1 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 3G6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

IMPDH1 Antibody (3G6) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: IMPDH1 (NP_000874, 201 a.a. ~ 300 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDC
• Specificity: IMPDH1 - IMP (inosine monophosphate) dehydrogenase 1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: IMPDH1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for IMPDH1 Antibody (3G6) - Azide and BSA Free

• DKFZp781N0678
• EC 1.1.1.205
• IMP (inosine 5'-monophosphate) dehydrogenase 1
• IMP (inosine monophosphate) dehydrogenase 1
• IMP Dehydrogenase 1
• IMPD 1
• IMPD
• IMPD1
• IMPDH 1
• IMPDH1
• IMPDH-I
• inosine-5'-monophosphate dehydrogenase 1
• LCA11
• LCA11RP10
• retinitis pigmentosa 10 (autosomal dominant)
• RP10
• sWSS2608

Background

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IMPDH1 Antibody (H00003614-M01)(3)

Publications using H00003614-M01

• Ouchida M, Kanzaki H, Ito S et al. Novel direct targets of miR-19a identified in breast cancer cells by a quantitative proteomic approach. PLoS One. 2012-01-01 [PMID: 22952885] (WB, Human)
• Zhang L, Iyer J, Chowdhury A et al. KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis. J Biol Chem. 2012-10-05 [PMID: 22904328] (WB, Human)
• Batovska DI, Kim DH, Mitsuhashi S et al. Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level. Biosci Biotechnol Biochem. 2008-10-07 [PMID: 18838793]

FAQs for IMPDH1 Antibody (H00003614-M01). (Showing 1 - 1 of 1 FAQs).

1. Do you have a kit for measuring IMPDH activity?
   • We currently do not have any kits to measure IMPDH activity, however we have a number of IMPDH antibody pairs that can be used for WB/IP and ELISA.

Bioinformatics

• Gene Symbol: IMPDH1
• Entrez:
  • 3614(Human)
• OMIM:
  • 146690(Human)
• Uniprot:
  • NP_000874(Human)