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IMPDH1 is encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
![Western Blot IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/IMP_Dehydrogenase_1_AF8554_Western_Blot_16658.jpg)
![Immunocytochemistry IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/IMP_Dehydrogenase_1_AF8554_Immunocytochemistry__Immunofluorescence_17605.jpg)
![Immunocytochemistry IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af8554_human-mouse-rat-imp-dehydrogenase-1-impdh1-aff-pur-pab-immunocytochemistry-842022162057.jpg)
![Simple Western IMPDH1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af8554_human-mouse-rat-imp-dehydrogenase-1-impdh1-aff-pur-pab-simple-western-1342022153711.jpg)
