ILT8/CD85b/LILRA6 Antibody (921330) [Unconjugated]

HEK293 human embryonic kidney cell line transfected with human LILRA6/CD85b and eGFP were stained with either (A) Mouse Anti-Human LILRA6/CD85b Monoclonal Antibody (Catalog # MAB8656) or (B) Mouse IgG1 Isotype Control (Catalog # MAB002) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human LILRA6/CD85b Monoclonal Antibody (Catalog # MAB8656, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 921330
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

ILT8/CD85b/LILRA6 Antibody (921330) [Unconjugated] Summary

• Immunogen: HEK293 human embryonic kidney cell line-derived recombinant human LILRA6/CD85b
  Met1-Asn447
  Accession # Q6PI73
• Specificity: Detects human LILRA6/CD85b in direct ELISA. Detects HEK293 cells transfected with LILRA6/CD85b but not irrelevant transfectants.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: LILRA6
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT8/CD85b/LILRA6 Antibody (921330) [Unconjugated]

• 7M1
• CD85b
• CD85b;ILT5;ILT8;ILT-8;LILRB3;LILRB6
• ILT8
• LILRA6
• Pira3

Background

LILRA6 (Leukocyte immunoglobulin-like receptor subfamily A, member 6) is also known as ILT5 and CD85b.   The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains. They are also known as ILTs and can exert immunomodulatory effects on a wide range of immune cells. LILRA6 is a highly polymorphic surface molecule that is one of the targets of dendritic cell-reactive antibodies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LILRA6
• Uniprot:
  • Q6PI73()