ILT6/CD85e/LILRA3 Antibody (293106) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB
• Clone: 293106
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

ILT6/CD85e/LILRA3 Antibody (293106) [Alexa Fluor® 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e
  Arg18-Glu439
  Accession # Q8N6C8
• Specificity: Detects human LILRA3/CD85e in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT1, 2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ILT6/CD85e/LILRA3 Antibody (293106) [Alexa Fluor® 488]

• CD85 antigen-like family member E
• CD85e antigen
• CD85e
• HM31
• HM43
• ILT6
• ILT-6
• ILT6CD85e
• Immunoglobulin-like transcript 6
• leucocyte immunoglobulin-like receptor
• Leukocyte immunoglobulin-like receptor 4
• leukocyte immunoglobulin-like receptor A3
• leukocyte immunoglobulin-like receptor subfamily A member 3
• leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member3
• LILRA3
• LIR4
• LIR4CD85E
• LIR-4HM43e3
• Monocyte inhibitory receptor HM43/HM31

Background

ILT6, also known as CD85e, LIR4, and LILRA3, contains four Ig-like C2-type domains and is the only ILT family member that lacks a transmembrane and cytoplasmic domain. ILT proteins modulate immune responses through interactions with class I MHC molecules. Several polymorphisms of ILT6 have been described, and loss of ILT6 is associated with the development of multiple sclerosis. Human and chimpanzee ILT6 share 84% amino acid sequence identity. ILT6 orthologs have not been described in other species.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q8N6C8()