IkB-epsilon Antibody (418515) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB
• Clone: 418515
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

IkB-epsilon Antibody (418515) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human IkB-ε
  Ser64-Asp423
  Accession # Q96F31
• Specificity: Detects endogenous human and mouse IkB-epsilon in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IkB-epsilon Antibody (418515) [Alexa Fluor® 405]

• epsilon
• ikappaBepsilon
• I-kappa-B-epsilon
• IkB-E
• IKBENF-kappa-B inhibitor epsilon
• IkBepsilon
• IkB-epsilon
• NF-kappa-BIE
• NFKBIE
• nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor

Background

NF kappa B inhibitor epsilon (IkB epsilon ) inhibits the NF kappa B complex by binding and sequestering it in the cytoplasm. Upon stimulation, IkB epsilon is phosphorylated on serine residues marking it for degradation by the ubiquitin pathway. Following IkB epsilon degradation, the NF kappa B complex is able to translocate to the nucleus and activate transcription.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.