Feline IgG Isotype Control [Alkaline Phosphatase]

Product Discontinued

Feline IgG Isotype Control [Alkaline Phosphatase] Summary

• Description: This Feline IgG immunoglobulin is useful as an isotype control for Feline IgG antibody.
• Specificity: Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Feline IgG, anti-Feline Serum and anti-Alkaline Phosphatase (calf intestine).
• Isotype: IgG
• Host: Feline
• Gene: IGHG1
• Purity: Ion exchange chromatography

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 0.05 M Tris Chloride, 0.15M Sodium Chloride, 0.001M Magnesium Chloride, 0.0001M Zinc Chloride, 50% (v/v) Glycerol; pH 8.0
• Preservative: No Preservative
• Purity: Ion exchange chromatography

Alternate Names for Feline IgG Isotype Control [Alkaline Phosphatase]

• IgG
• Immunoglobulin G
• ImmunoglobulinG

Background

IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. This is the only isotype that can pass through the human placenta, thereby providing protection to the fetus in its first weeks of life before its own immune system has developed. It can bind to many kinds of pathogens, for example viruses, bacteria, and fungi, and protects the body against them by complement activation (classic pathway), opsonization for phagocytosis and neutralisation of their toxins. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Isotype Controls are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IGHG1