IFN-beta Antibody [Unconjugated]

• Reactivity: Hu
• Applications: B/N
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

IFN-beta Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human IFN-beta
• Specificity: Detects Human IFN‑ beta
• Source: N/A
• Isotype: Serum
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IFNB1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Neutralization

Packaging, Storage & Formulations

• Storage: After receipt, this product should be kept at -70 ˚C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed – the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
• Buffer: Serum.
• Preservative: No Preservative

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-beta Antibody [Unconjugated]

• Fibroblast interferon
• IFB
• IFBIFNB
• IFF
• IFNB
• IFNB1
• IFNbeta
• IFN-beta
• interferon beta
• interferon, beta 1, fibroblast
• MGC96956

Background

Interferon-beta (IFN-beta), along with IFN-alpha and IFN-omega, is a member of the type I interferon family. All three type I interferons share a common cell surface receptor that is composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. Type I interferons were originally described as potent anti-viral molecules produced by virally infected cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IFN-beta Antibody (31410-1)(2)

Publications using 31410-1

• Patel MV, Ghosh M, Fahey JV, Wira CR Uterine epithelial cells specifically induce interferon-stimulated genes in response to polyinosinic-polycytidylic acid independently of estradiol. PLoS ONE, 2012-04-25;7(4):e35654. 2012-04-25 [PMID: 22558189] (Neutralization, Human)
• Lee SH, Kim JS, Jun HK The major outer membrane protein of a periodontopathogen induces IFN-beta and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor-3. J. Immunol., 2009-05-01;182(9):5823-35. 2009-05-01 [PMID: 19380831] (Neutralization, Human)

Bioinformatics

• Gene Symbol: IFNB1