IFN-beta Antibody [Unconjugated]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications B/N
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated

Order Details

IFN-beta Antibody [Unconjugated] Summary

Immunogen
Recombinant human IFN‑ beta 1a (expressed in mammalian cells)
Specificity
Detects human IFN‑ beta.
Source
N/A
Isotype
Serum
Clonality
Polyclonal
Host
Sheep
Gene
IFNB1
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Applications/Dilutions

Dilutions
  • Neutralization

Packaging, Storage & Formulations

Storage
After receipt, the product may be stored at -20°C for short-term use (≤ 6 months). For long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
Buffer
Neat serum.
Preservative
No Preservative

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-beta Antibody [Unconjugated]

  • Fibroblast interferon
  • IFBIFNB
  • IFF
  • IFNB1
  • IFNbeta
  • IFN-beta
  • interferon beta
  • interferon, beta 1, fibroblast
  • MGC96956

Background

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for IFN-beta Antibody (31401-1)

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Diseases for IFN-beta Antibody (31401-1)

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Pathways for IFN-beta Antibody (31401-1)

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Blogs on IFN-beta.

STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also...  Read full blog post.

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Contact Information

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Bioinformatics

Gene Symbol IFNB1
Entrez