IFIT3 Antibody [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 610 SE

IFIT3 Antibody [mFluor Violet 610 SE] Summary

• Immunogen: IFIT3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT3. The immunogen is located within amino acids 380 - 430 of IFIT3 .
• Specificity: IFIT3 antibody is human specific. This antibody is predicted to not cross-react with other members of the IFIT protein family.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IFIT3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IFIT3 Antibody [mFluor Violet 610 SE]

• CIG-49
• GARG-49
• IFI60Retinoic acid-induced gene G protein
• IFIT-3
• IFIT-4
• IFIT4IFI-60K
• interferon-induced protein with tetratricopeptide repeats 3
• Interferon-induced protein with tetratricopeptide repeats 4Interferon-induced 60 kDa protein
• IRG2
• ISG60
• ISG-60
• RIG-GCIG49

Background

IFIT3, also known as IFIT4, IFI60, and RIGG, has been identified as a key element in the IFN-alpha anti-viral pathway. Additionally, IFIT3 binding negatively regulates the apoptotic effects of ISG54. IFIT3 is also a key target of STAT1, which is important in regulating IFN responses. One study has shown that expression of RIGG in a human monocytoma line led to growth arrest at the G1/S transition.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IFIT3