ICAM-2/CD102 Antibody (86911) [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Clone: 86911
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

ICAM-2/CD102 Antibody (86911) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human ICAM‑2/CD102 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) CEACAM-1, recombinant mouse (rm) DCC, rhICAM-1, rmICAM-2, rhICAM-3, rmICAM-5, rmMAdCAM-1, rhCD31, or rmVCAM-1 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ICAM-2/CD102 Antibody (86911) [Alexa Fluor™ Plus 555]

• CD102 antigen
• CD102
• ICAM2
• ICAM-2
• intercellular adhesion molecule 2

Background

Intercellular Adhesion Molecule-2 (ICAM-2, CD102), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). ICAM-2 is constitutively expressed at high levels on vascular endothelial cells and lymphohematopoietic cells. ICAM-2 mediated adhesion has been shown to provide a co-stimulatory signal for T cell aggregation, NK cytotoxicity and NK cell migration.

1. Somersalo, K. et al. (1995) J. Biol. Chem. 270:8629.
2. Hayflick, J. et al. (1998) Immunologic Res. 17:313.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.