uPAR Products

Antibodies
uPAR Antibody (62022) [Unconj ...
uPAR Antibody (62022) [Unconjugated]
MAB807
Species: Hu
Applications: WB, Flow, Block, CyTOF-ready, ELISA(Cap)
Host: Mouse Monoclonal
uPAR Antibody [Unconjugated]
uPAR Antibody [Unconjugated]
AF534
Species: Mu
Applications: WB, Flow, IHC, Block, CyTOF-ready
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
uPAR Antibody [Unconjugated]
uPAR Antibody [Unconjugated]
AF807
Species: Hu
Applications: WB, IP, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Human uPAR ELISA Kit (Colorim ...
Human uPAR ELISA Kit (Colorimetric)
KA0426
Species: Hu
Applications: ELISA
Lysates
uPAR Overexpression Lysate (N ...
uPAR Overexpression Lysate (Native)
NBL1-14487
Applications: WB
Proteins
Recombinant Human uPAR Protei ...
Recombinant Human uPAR Protein
807-UK
Species: Hu
Applications: Bind
Recombinant Mouse uPAR Fc Chi ...
Recombinant Mouse uPAR Fc Chimera ...
531-PA
Species: Mu
Applications: Bind
uPAR Recombinant Protein Anti ...
uPAR Recombinant Protein Antigen
NBP2-14711PEP
Species: Hu
Applications: AC

Description

uPAR (Urokinase plasminogen activator receptor) is a glycoprotein I anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta globulin plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Mouse
Product By Gene ID 5329
Alternate Names
  • U-PAR
  • uPAR
  • Monocyte activation antigen Mo3
  • CD87 antigen
  • CD87
  • URKRMO3
  • UPARurokinase plasminogen activator surface receptor
  • u-plasminogen activator receptor form 2
  • plasminogen activator, urokinase receptor

Research Areas for uPAR

Find related products by research area and learn more about each of the different research areas below.

Cancer

Bioinformatics Tool for uPAR

Discover related pathways, diseases and genes to uPAR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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