Human uPAR DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human uPAR DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: PLAUR

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human uPAR DuoSet ELISA, 15 Plate

• CD87 antigen
• CD87
• Monocyte activation antigen Mo3
• plasminogen activator, urokinase receptor
• PLAUR
• uPAR
• U-PAR
• UPARurokinase plasminogen activator surface receptor
• u-plasminogen activator receptor form 2
• URKRMO3

Background

The urokinase-type Plasminogen Activator Receptor (uPAR) is a GPI-anchored protein that binds to both the inactive and active forms of uPA. This interaction serves to localize and enhance the proteolytic activity of uPA, leading to increased conversion of Plasminogen to Plasmin. uPA also triggers uPAR-mediated signal transduction, activation of protein tyrosine kinases, gene expression, cell adhesion, and chemotaxis. uPAR can additionally regulate cell adhesion by direct binding to Vitronectin and preventing Integrins from binding to their ligands.

Publications for uPAR (DY807)(14)

Publications using DY807

• Ohnewein, B;Shomanova, Z;Jirak, P;Paar, V;Topf, A;Pylypenko, L;Schäbinger, M;Volg, F;Hoppe, UC;Pistulli, R;Zagidullin, N;Lichtenauer, M;Motloch, LJ; Dynamics of the Novel Cardiac Biomarkers sST2, H-FABP, GDF-15 and suPAR in HFrEF Patients Undergoing Heart Failure Therapy, a Pilot Study Journal of clinical medicine 2025-08-11 [PMID: 40869494] (Human)
• Fröhling, T;Semo, D;Mirna, M;Paar, V;Shomanova, Z;Motloch, LJ;Rukosujew, A;Sindermann, JR;Lichtenauer, M;Pistulli, R; Novel Biomarkers as Potential Predictors of Decompensated Advanced Chronic Heart Failure-Single Center Study Journal of clinical medicine 2024-11-14 [PMID: 39598008] (Human)
• Sereti, I;Verburgh, ML;Gifford, J;Lo, A;Boyd, A;Verheij, E;Verhoeven, A;Wit, FWNM;Schim van der Loeff, MF;Giera, M;Kootstra, NA;Reiss, P;Vujkovic-Cvijin, I; Impaired gut microbiota-mediated short-chain fatty acid production precedes morbidity and mortality in people with HIV Cell reports 2023-10-30 [PMID: 37918403] (Human)
• J Kletzer, S Hecht, S Ramsauer, B Scharinger, R Kaufmann, J Kammler, J Kellermair, K Akbari, H Blessberge, C Steinwende, K Hergan, UC Hoppe, M Lichtenaue, E Boxhammer A Story of PA/BSA and Biomarkers to Diagnose Pulmonary Hypertension in Patients with Severe Aortic Valve Stenosis-The Rise of IGF-BP2 and GDF-15 Journal of cardiovascular development and disease, 2023-01-05;10(1):. 2023-01-05 [PMID: 36661917] (Human)
• S Hecht, E Boxhammer, R Kaufmann, B Scharinger, C Reiter, J Kammler, J Kellermair, M Hammerer, H Blessberge, C Steinwende, UC Hoppe, K Hergan, M Lichtenaue CT-Diagnosed Sarcopenia and Cardiovascular Biomarkers in Patients Undergoing Transcatheter Aortic Valve Replacement: Is It Possible to Predict Muscle Loss Based on Laboratory Tests?-A Multicentric Retrospective Analysis Journal of personalized medicine, 2022-09-04;12(9):. 2022-09-04 [PMID: 36143238] (Human)
• S Mogren, F Berlin, L Eskilsson, N Van Der Bu, E Tufvesson, CK Andersson Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells Cells, 2022-09-18;11(18):. 2022-09-18 [PMID: 36139491] (Human)
• MC Chang, NY Chen, JH Chen, WL Huang, CY Chen, CC Huang, YH Pan, HH Chang, JH Jeng bFGF stimulated plasminogen activation factors, but inhibited alkaline phosphatase and SPARC in stem cells from apical Papilla: Involvement of MEK/ERK, TAK1 and p38 signaling Oncogene, 2021-12-28;40(0):95-107. 2021-12-28 [PMID: 36100336] (Human)
• R Fernandez-, YZ Szabo, KB Lyle, TL Newton The levels of soluble urokinase plasminogen activator receptor (suPAR) in saliva are influenced by acute stress Biological psychology, 2021-09-04;165(0):108147. 2021-09-04 [PMID: 34492333] (Human)
• R Fernandez-, MW Plankey, D Ware, J Bordon Changes in liver steatosis in HIV-positive women are associated with the BMI, but not with biomarkers Cytokine, 2021-05-12;0(0):155573. 2021-05-12 [PMID: 33994069] (Human)
• C Amor, J Feucht, J Leibold, YJ Ho, C Zhu, D Alonso-Cur, J Mansilla-S, JA Boyer, X Li, T Giavridis, A Kulick, S Houlihan, E Peerschke, SL Friedman, V Ponomarev, A Piersigill, M Sadelain, SW Lowe Senolytic CAR T cells reverse senescence-associated pathologies Nature, 2020-06-17;0(0):. 2020-06-17 [PMID: 32555459] (Human)
• CA Valle Oseg, JV Spencer Human cytomegalovirus interleukin-10 enhances matrigel invasion of MDA-MB-231 breast cancer cells Cancer Cell Int, 2017-02-13;17(0):24. 2017-02-13 [PMID: 28228690] (Human)
• Portelli M, Siedlinski M, Stewart C, Postma D, Nieuwenhuis M, Vonk J, Nurnberg P, Altmuller J, Moffatt M, Wardlaw A, Parker S, Connolly M, Koppelman G, Sayers I Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB J, 2013-11-18;28(2):923-34. 2013-11-18 [PMID: 24249636] (Human)
• Barton SJ, Koppelman GH, Vonk JM, Browning CA, Nolte IM, Stewart CE, Bainbridge S, Mutch S, Rose-Zerilli MJ, Postma DS, Maniatis N, Henry AP, Hall IP, Holgate ST, Tighe P, Holloway JW, Sayers I PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline. J. Allergy Clin. Immunol., 2009-05-13;123(6):1391-400.e17. 2009-05-13 [PMID: 19443020] (Human)
• Wu T, Xie C, Wang HW, Zhou XJ, Schwartz N, Calixto S, Mackay M, Aranow C, Putterman C, Mohan C Elevated urinary VCAM-1, P-selectin, soluble TNF receptor-1, and CXC chemokine ligand 16 in multiple murine lupus strains and human lupus nephritis. J. Immunol., 2007-11-15;179(10):7166-75. 2007-11-15 [PMID: 17982109] (Human)

FAQs for uPAR (DY807). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: PLAUR