Human PSG1 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human PSG1 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human PSG1 DuoSet ELISA, 5 Plate

• B1G1
• B1G1CD66 antigen-like family member F
• CD66f antigen
• CD66f
• DHFRP2
• Fetal liver non-specific cross-reactive antigen 1/2
• FLJ90598
• FLJ90654
• FL-NCA-1/2
• PBG1
• pregnancy specific beta-1-glycoprotein 1
• pregnancy-specific B-1 glycoprotein
• Pregnancy-specific beta-1 glycoprotein C/D
• pregnancy-specific beta-1-glycoprotein 1
• Pregnancy-specific glycoprotein 1
• PS-beta-C/D
• PS-beta-G-1
• PSbG1
• PSBG-1
• PSBG1SP1
• PSG1
• PSG-1
• PSG95
• PSGGA
• PSGGAPSG95
• PSGIIA

Background

Pregnancy-specific beta-1 glycoprotein 1 (PSG-1) is also known as SP1, PSbG1, or B1G1, and is designated CD66f. PSGs are part of the carcinoembryonic antigen (CEA) family and serve as early biochemical markers of syncytiotrophoblast formation. PSGs, which are produced by syncytial cells in the placenta, are detectable in the maternal plasma as early as 2-3 weeks following fertilization and increase as pregnancy progresses. They are alleged to promote immune tolerance of the semi-allotypic fetus during pregnancy. PSG-1 fosters an anti-inflammatory uterine environment by inducing IL-10, IL-6, and TGF-beta 1 secretion. Additionally, PSG-1 is believed to mediate placental vascular morphogenesis by enhancing VEGF-A production and endothelial tube formation.

Publications for PSG1 (DY6799-05)(1)

Publication using DY6799-05

• Cho, HY;Lee, JE;Park, KH;Choi, BY;Lee, MJ;Jeong, DE;Shin, S; Identification and characterization of plasma proteins associated with intra-amniotic inflammation and/or infection in women with preterm labor. Scientific reports 2024-06-25 [PMID: 38918423] (Human)