Human Osteocalcin Quantikine ELISA Kit

Product Discontinued

Human Osteocalcin Quantikine ELISA Kit Summary

• Background: The Quantikine Human Osteocalcin Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human Osteocalcin in cell culture supernates and EDTA plasma. It contains synthetic human Osteocalcin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Osteocalcin showed linear curves that were parallel to the standard curves obtained using ...the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human Osteocalcin.
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• Additional Information: Product is in the process of discontinuation. Please consider catalog # DY1419-05 as an alternative.
• Specificity: Natural and recombinant human Osteocalcin.
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: BGLAP

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Osteocalcin Quantikine ELISA Kit

• BGLAP
• BGP
• bone gamma-carboxyglutamate (gla) protein (osteocalcin)
• bone gamma-carboxyglutamate (gla) protein
• Bone Gla protein
• Gamma-carboxyglutamic acid-containing protein
• OC
• OCN
• Osteocalcin

Background

Osteocalcin, also named Bone gamma-carboxyglutamic Acid Protein, is a secreted protein whose expression is restricted to cells of the osteoblast lineage. It has been frequently used as a marker for osteoblast lineage cells.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Osteocalcin (DSTCN0)(14)

Publications using DSTCN0

• J Jarecki, T Ma?ecka-Ma, E Kosior-Jar, W Widuchowsk, P Krasowski, M Gutbier, M Dobrzy?ski, T Blicharski Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis International Journal of Environmental Research and Public Health, 2022-03-16;19(6):. 2022-03-16 [PMID: 35329213] (Human)
• X Du, C Zhang, X Zhang, Z Qi, S Cheng, S Le The Impact of Nordic Walking on Bone Properties in Postmenopausal Women with Pre-Diabetes and Non-Alcohol Fatty Liver Disease International Journal of Environmental Research and Public Health, 2021-07-16;18(14):. 2021-07-16 [PMID: 34300021] (Human)
• R Khwanchuea, C Punsawad Sex differences in the relationship between body composition and biomarkers of bone and fat metabolism in obese boys and girls Bone Reports, 2021-05-04;14(0):101087. 2021-05-04 [PMID: 34026951] (Human)
• S Camarero-E, L Moroni Janus 3D printed dynamic scaffolds for nanovibration-driven bone regeneration Nature Communications, 2021-02-15;12(1):1031. 2021-02-15 [PMID: 33589620] (Human)
• JI Aguayo-Rui, TA García-Cob, S Pascoe-Gon, S Sánchez-En, IM Llamas-Cov, T García-Igl, A López-Quin, MA Llamas-Cov, J Trujillo-Q, EA Rivera-Leo Effect of supplementation with vitamins D3 and K2 on undercarboxylated osteocalcin and insulin serum levels in patients with type 2 diabetes mellitus: a randomized, double-blind, clinical trial Diabetol Metab Syndr, 2020-08-18;12(0):73. 2020-08-18 [PMID: 32831908] (Human)
• RC Fernando, DR Mazzotti, H Azevedo, AF Sandes, EG Rizzatti, MB de Oliveir, VLF Alves, AIP Eugênio, F de Carvalh, MA Dalboni, DC Martins, GWB Colleoni Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism Sci Rep, 2019-01-31;9(1):1056. 2019-01-31 [PMID: 30705326] (Human)
• O Catanzano, A Soriente, A La Gatta, M Cammarota, G Ricci, I Fasolino, C Schiraldi, L Ambrosio, M Malinconic, P Laurienzo, MG Raucci, G Gomez d'Ay Macroporous alginate foams crosslinked with strontium for bone tissue engineering Carbohydr Polym, 2018-08-23;202(0):72-83. 2018-08-23 [PMID: 30287045] (Human)
• IA Paun, RC Popescu, BS Calin, CC Mustaciosu, M Dinescu, CR Luculescu 3D Biomimetic Magnetic Structures for Static Magnetic Field Stimulation of Osteogenesis Int J Mol Sci, 2018-02-07;19(2):. 2018-02-07 [PMID: 29414875] (Human)
• JL Kelleher, DP Beavers, RM Henderson, D Yow, C Crotts, J Kiel, BJ Nicklas, KM Beavers Weighted Vest Use during Dietary Weight Loss on Bone Health in Older Adults with Obesity J Osteoporos Phys Act, 2017-11-28;5(4):. 2017-11-28 [PMID: 29388604] (Human)
• Kumar B, Garcia M, Weng L, Jung X, Murakami J, Hu X, McDonald T, Lin A, Kumar A, DiGiusto D, Stein A, Pullarkat V, Hui S, Carlesso N, Kuo Y, Bhatia R, Marcucci G, Chen C Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion. Leukemia, 2017-08-17;32(3):575-587. 2017-08-17 [PMID: 28816238] (Human)
• Q Guo, H Li, L Xu, S Wu, H Sun, B Zhou Undercarboxylated osteocalcin reverts insulin resistance induced by endoplasmic reticulum stress in human umbilical vein endothelial cells Sci Rep, 2017-03-03;7(1):46. 2017-03-03 [PMID: 28246389] (Human)
• Choknapa Tirachaimo Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study Int J Implant Dent, 2016-12-08;2(1):27. 2016-12-08 [PMID: 27933572] (Human)
• Identification of suitable reference gene and biomarkers of serum miRNAs for osteoporosis Sci Rep, 2016-11-08;6(0):36347. 2016-11-08 [PMID: 27821865] (Primate - Macaca mulatta (Rhesus Macaque))
• Yu J, Li K, Zheng X, He D, Ye X, Wang M In vitro and in vivo evaluation of zinc-modified ca-si-based ceramic coating for bone implants. PLoS ONE, 2013-03-06;8(3):e57564. 2013-03-06 [PMID: 23483914] (Mouse)

FAQs for Osteocalcin (DSTCN0). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: BGLAP