Human Fas/TNFRSF6/CD95 Quantikine ELISA Kit

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Human Fas/TNFRSF6/CD95 Quantikine ELISA Kit Summary

Background
The Quantikine Human sFas Immunoassay is a 4.5 hour solid phase ELISA designed to measure human sFas in cell culture supernates, serum, and plasma. It contains recombinant human Fas/Fc chimera expressed from NS0 cells and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained measuring natural human ...sFas showed dose-response curves that were parallel to the standard curves obtained using the recombinant Fas/Fc chimera. These results indicate that this kit can be used to determine relative mass values for natural human sFas.
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Specificity
Natural and recombinant human sFas
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
FAS

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DFS00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Fas/TNFRSF6/CD95 Quantikine ELISA Kit

  • Apo-1 antigen
  • Apo-1
  • apoptosis antigen 1
  • Apoptosis-mediating surface antigen FAS
  • APT1
  • APT1FASTM
  • CD95 antigen
  • CD95
  • CD95ALPS1A
  • Fas (TNF receptor superfamily, member 6)
  • Fas AMA
  • Fas antigen
  • Fas
  • FAS1
  • FASLG receptor
  • TNFRSF6
  • TNFRSF6member 6
  • tumor necrosis factor receptor superfamily member 6

Background

Fas (Fibroblast-associated), also known as Apo-1, CD95, and TNFRSF6, was originally identified as a cell-surface protein that binds to monoclonal antibodies that are cytolytic for various human cell lines. Alternatively spliced cDNAs encoding multiple Fas isoforms, including a soluble form of Fas, have been identified. Fas is highly expressed in epithelial cells, hepatocyes, activated mature lymphocytes, virus-transformed lymphocytes and other tumor cells. Fas expression has also been detected in mouse thymus, liver, heart, lung, kidney and ovary.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for Fas/TNFRSF6/CD95 (DFS00)(17)

We have publications tested in 1 confirmed species: Human.


Filter By Application
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Human
(17)
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Showing Publications 1 - 10 of 17. Show All 17 Publications.
Publications using DFS00 Applications Species
R Grzanka, A Damasiewic, A Kasperska- Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria Allergy Asthma Clin Immunol, 2019;15(0):15. 2019 [PMID: 30911316] (Human) Human
A Karowicz-B, U Kowalska-K, D Estemberg, A Sikora-Szu Evaluation of soluble concentration Fas and Fas ligand in maternal and cord blood 3rd trimester of pregnancy Ginekol. Pol., 2018;89(3):142-146. 2018 [PMID: 29664549] (Human) Human
Sehgal, L, Mathur, R, Braun, F K, Wise, J F, Berkova, Z, Neelapu, S, Kwak, L W, Samaniego, F FAS-antisense 1 lncRNA and production of soluble versus membrane Fas in B-cell lymphoma. Leukemia, 2014;28(12):2376-87. 2014 [PMID: 24811343] (Human) Human
Chang J, Zhang G, Zhang L, Hou Y, Liu X, Zhang L High admission glucose levels increase Fas apoptosis and mortality in patients with acute ST-elevation myocardial infarction: a prospective cohort study. Cardiovasc Diabetol, 2013;12(1):171. 2013 [PMID: 24229414] (Human) Human
Deftereos S, Giannopoulos G, Kossyvakis C, Kaoukis A, Raisakis K, Driva M, Panagopoulou V, Lappos S, Rentoukas I, Pyrgakis V, Alpert MA Effect of quinapril on in-stent restenosis and relation to plasma apoptosis signaling molecules. Am. J. Cardiol., 2010;105(1):54-8. 2010 [PMID: 20102890] (Human) Human
Zhao WS, Xu L, Wang LF, Zhang L, Zhang ZY, Liu Y, Liu XL, Yang XC, Cui L, Zhang L A 60-s postconditioning protocol by percutaneous coronary intervention inhibits myocardial apoptosis in patients with acute myocardial infarction. Apoptosis, 2009;14(10):1204-11. 2009 [PMID: 19693675] (Human) Human
Fas expression in conjunctival epithelial cells of patients with cystic fibrosis. J. Interferon Cytokine Res., 2009;29(11):735-40. 2009 [PMID: 19642903] (Human) Human
Niessner A, Hohensinner PJ, Rychli K, Neuhold S, Zorn G, Richter B, Hulsmann M, Berger R, Mortl D, Huber K, Wojta J, Pacher R Prognostic value of apoptosis markers in advanced heart failure patients. Eur. Heart J., 2009;30(7):789-96. 2009 [PMID: 19196721] (Human) Human
Perez-Andres M, Almeida J, Martin-Ayuso M, De Las Heras N, Moro MJ, Martin-Nunez G, Galende J, Cuello R, Abuin I, Moreno I, Dominguez M, Hernandez J, Mateo G, San Miguel JF, Orfao A Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease. Int. J. Cancer, 2009;124(2):367-75. 2009 [PMID: 19003959] (Human) Human
Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure. Atherosclerosis, 2007;199(1):215-21. 2007 [PMID: 17991471] (Human) Human
Show All 17 Publications.

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Product General Protocols

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FAQs for Fas/TNFRSF6/CD95 (DFS00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DFS00

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Bioinformatics

Gene Symbol FAS