Human DLL4 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human DLL4 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human DLL4 DuoSet ELISA, 5 Plate

• Delta 4 precursor
• delta 4
• delta ligand 4
• delta4
• delta-like 4 (Drosophila)
• delta-like 4 homolog (Drosophila)
• delta-like 4 homolog
• delta-like 4 protein
• delta-like protein 4
• DLL4
• Drosophila Delta homolog 4
• hdelta2
• MGC126344
• notch ligand delta-2
• notch ligand DLL4

Background

Delta-like protein 4 (DLL4) is a transmembrane protein in the Delta/Serrate/Lag2 (DSL) family of Notch ligands. It is selectively expressed on arterial endothelial cells and functions as a ligand for Notch 1 and Notch 4. Notch signaling controls cell fate and is required during vascular development, hematopoiesis, somatogenesis, myogenesis, and neurogenesis. DLL4 interaction with Notch proteins triggers the proteolysis of both molecules, with release the intracellular and extracellular domains and subsequent regulation of gene transcription.

Publications for DLL4 (DY1506-05)(1)

Publication using DY1506-05

• Mudra Rakshasa-Loots, A;Naidoo, S;Hamana, T;Fanqa, B;van Wyhe, KS;Lindani, F;van der Kouwe, AJW;Glashoff, R;Kruger, S;Robertson, F;Cox, SR;Meintjes, EM;Laughton, B; Multi-modal analysis of inflammation as a potential mediator of depressive symptoms in young people with HIV: The GOLD depression study PloS one 2024-02-22 [PMID: 38386679] (Human)

FAQs for DLL4 (DY1506-05). (Showing 1 - 1 of 1 FAQ).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.