Human CCL7/MCP-3 Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human CCL7/MCP-3 Quantikine ELISA Kit Summary

• Background: The Quantikine Human MCP-3 Immunoassay is a 4.5 hour solid phase ELISA designed to measure MCP-3 levels in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human MCP-3 and antibodies raised against the recombinant factor. Results obtained for naturally occurring human MCP-3 showed linear curves that were parallel to the standard curves obtained u...sing the kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MCP-3.
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• Specificity: Natural and recombinant human MCP-3
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CCL7

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL7/MCP-3 Quantikine ELISA Kit

• C-C motif chemokine 7
• CCL7
• chemokine (C-C motif) ligand 7
• FIC
• MARC
• MCP-3
• MCP3Monocyte chemotactic protein 3
• MCP-3Small-inducible cytokine A7
• MGC138465
• Monocyte chemoattractant protein 3
• NC28SCYA6
• SCYA7MGC138463
• small inducible cytokine A7 (monocyte chemotactic protein 3)

Background

Human MCP-3 and mouse MARC are members of the CC subfamily of chemokines and are monocyte chemoattractants. Sequence comparisons suggest that MARC may be the mouse homolog of the human MCP-3 gene. Except for one amino acid subsititution, mouse MARC is identical to mouse FIC, the product of a growth factor-activated gene.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL7/MCP-3/MARC (DCC700)(13)

Publications using DCC700

• F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells bioRxiv : the preprint server for biology, 2023-02-13;0(0):. 2023-02-13 [PMID: 36789428] (Human)
• N Komabashir, F Suehiro, M Ishii, M Nishimura Efficacy of chitinase-3-like protein 1 as an in�vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells Regenerative Therapy, 2021-03-27;18(0):38-50. 2021-03-27 [PMID: 33869686] (Human)
• P Cao, NM Walker, RR Braeuer, S Mazzoni-Pu, Y Aoki, K Misumi, DS Wheeler, R Vittal, VN Lama Loss of FOXF1 expression promotes human lung-resident mesenchymal stromal cell migration via ATX/LPA/LPA1 signaling axis Scientific Reports, 2020-12-04;10(1):21231. 2020-12-04 [PMID: 33277571] (Human)
• MVC Rudge, FP Souza, JF Abbade, RLS Hallur, JPC Marcondes, F Piculo, G Marini, G Vesentini, L Thabane, SS Witkin, IMP Calderon, AMP Barbosa, MV Rudge, AMP Barbosa, IMP Calderon, FP Souza, JF Abbade, LSR Hallur, F Piculo, G Marini, G Vesentini, L Thabane, MS Palma, CFO Graeff, RK Arni, RD Herculano, DF Salvadori, S Mateus, M Dal Pai Si, CG Magalhães, RA Costa, SAM Lima, SL Felisbino, W Barbosa, A Atallah, MJB Girão, Z Di Bella, SM Uchoa, S Payão, A Hijas, B Berghman, R De Bie, L Sobrevia, B Junginger, FCB Alves, PS Rossignoli, CB Prudencio, MIG Orlandi, MI Gonçalves, SK Nunes, BB Catinelli, S Quiroz, BV Sarmento, FA Pinheiro, CI Sartorão, RR Lucas, DRA Reyes, SBCV Quiroz, EMA Enriquez, RG Oliveira, JF Floriano, JPC Marcondes, S Barneze, TD Dangió, T Pascon, P Rossignoli, JV Freitas, L Takano, F Reis, TD Caldeirão, JN Fernandes, AM Carr, MVC Gaitero, JE Corrente, HRC Nunes, AF Candido, SMB Costa, TD Dangió, T Pascon, JVF Melo, L Takano, FVDS Reis, TD Caldeirão, AM Carr, GA Garcia, GB Rabadan, HCM Bassin, KS Suyama, LN Damasceno, MLS Takemoto, MD Menezes, DG Bussaneli, VKC Nogueira, PR Lima, IO Lourenço, J Marostica, RA Megid, IP Caruso, LT Rasmussen, GM Prata, F Piculo, G Vesentini, MA Arantes, GAR Ferraz, LP Camargo, MR Kron, JE Corrente, HRC Nunes Study protocol to investigate biomolecular muscle profile as predictors of long-term urinary incontinence in women with gestational diabetes mellitus BMC Pregnancy Childbirth, 2020-02-19;20(1):117. 2020-02-19 [PMID: 32075598] (Human)
• Maddaluno M, Grassia G, Di Lauro M, Parisi A, Maione F, Cicala C, De Filippis D, Iuvone T, Guglielmotti A, Maffia P, Mascolo N, Ialenti A Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. PLoS ONE, 2012-10-15;7(10):e47464. 2012-10-15 [PMID: 23077623] (Human)
• Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int. J. Cancer, 2010-07-15;127(2):332-44. 2010-07-15 [PMID: 19937793] (Human)
• Ingvarsson J, Wingren C, Carlsson A, Ellmark P, Wahren B, Engstrom G, Harmenberg U, Krogh M, Peterson C, Borrebaeck CA Detection of pancreatic cancer using antibody microarray-based serum protein profiling. Proteomics, 2008-06-01;8(11):2211-9. 2008-06-01 [PMID: 18528842] (Human)
• Kang MJ, Homer RJ, Gallo A, Lee CG, Crothers KA, Cho SJ, Rochester C, Cain H, Chupp G, Yoon HJ, Elias JA IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation. J. Immunol., 2007-02-01;178(3):1948-59. 2007-02-01 [PMID: 17237446] (Human)
• Dame TM, Orenzoff BL, Palmer LE, Furie MB IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation. J. Immunol., 2007-01-15;178(2):1172-9. 2007-01-15 [PMID: 17202382] (Human)
• Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function. Blood, 2006-04-13;108(3):947-55. 2006-04-13 [PMID: 16614246] (Human)
• Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia. Am. J. Respir. Crit. Care Med., 2004-06-10;170(5):508-15. 2004-06-10 [PMID: 15191918] (Human)
• Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. J. Virol., 2004-06-01;78(12):6151-61. 2004-06-01 [PMID: 15163708] (Primate - Pan troglodytes (Chimpanzee))
• Ciesielski CJ, Andreakos E, Foxwell BM, Feldmann M TNFalpha-induced macrophage chemokine secretion is more dependent on NF-kappaB expression than lipopolysaccharides-induced macrophage chemokine secretion. Eur. J. Immunol., 2002-07-01;32(7):2037-45. 2002-07-01 [PMID: 12115625] (Human)

Bioinformatics

• Gene Symbol: CCL7