Human alpha 1-Acid Glycoprotein Quantikine ELISA Kit

• Reactivity: Hu
• Applications: ELISA
• Conjugate: HRP

Human alpha 1-Acid Glycoprotein Quantikine ELISA Kit Summary

• Background: The Quantikine Human AGP Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human AGP in cell culture supernates, serum, plasma, and urine.
• Specificity: Natural human AGP
• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: ORM1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human alpha 1-Acid Glycoprotein Quantikine ELISA Kit

• AGP 1
• AGP
• AGP1
• AGP1alpha-1-acid glycoprotein 1
• AGPA
• AGP-A
• alpha 1Acid Glycoprotein
• alpha 1-Acid Glycoprotein
• OMD 1
• ORM
• ORM1
• orosomucoid 1
• Orosomucoid
• orosomucoid-1

Background

Alpha 1-acid Glycoprotein (AGP), also known as Orosomucoid, is a Lipocalin family acute-phase protein that is produced by the liver in response to inflammation and infection. Its serum concentration can increase 2-5 fold, making it one of the predominant proteins in serum. AGP functions as a carrier protein for many basic and neutral lipophilic drugs including steroid hormones. It can inhibit neutrophil migration in sepsis, exert a protective effect in severe bacterial infection, and inhibit platelet aggregation. The glycosylation pattern of alpha 1-Acid Glycoprotein influences its anti-inflammatory properties and is associated with various pathophysiological states.

⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for alpha 1-Acid Glycoprotein (DAGP00)(6)

Publications using DAGP00

• HW Unger, A Bleicher, M Ome-Kaius, EH Aitken, SJ Rogerson Associations of maternal iron deficiency with malaria infection in a cohort of pregnant Papua New Guinean women Malaria Journal, 2022-05-26;21(1):153. 2022-05-26 [PMID: 35619134] (Human)
• HW Unger, V Laurita Lo, A Bleicher, M Ome-Kaius, S Karl, JA Simpson, A Karahalios, EH Aitken, SJ Rogerson The relationship between markers of antenatal iron stores and birth outcomes differs by malaria prevention regimen-a prospective cohort study Bmc Medicine, 2021-10-05;19(1):236. 2021-10-05 [PMID: 34607575] (Human)
• HW Unger, AP Hansa, C Buffet, W Hasang, A Teo, L Randall, M Ome-Kaius, S Karl, AA Anuan, JG Beeson, I Mueller, SJ Stock, SJ Rogerson Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection Sci Rep, 2019-02-19;9(1):2260. 2019-02-19 [PMID: 30783215] (Human)
• RH Bartels, E Chimwezi, V Watson, L Pei, I Potani, B Allubha, K Chidzalo, D Wang, Q Dube, M Mallewa, A Allen, RHJ Bandsma, WP Voskuijl, SJ Allen Hypoallergenic and anti-inflammatory feeds in children with complicated severe acute malnutrition: an open randomised controlled 3-arm intervention trial in Malawi Sci Rep, 2019-02-19;9(1):2304. 2019-02-19 [PMID: 30783173] (Human)
• Cepeda-Lopez A, Allende-Labastida J, Melse-Boonstra A, Osendarp S, Herter-Aeberli I, Moretti D, Rodriguez-Lastra R, Gonzalez-Salazar F, Villalpando S, Zimmermann M The effects of fat loss after bariatric surgery on inflammation, serum hepcidin, and iron absorption: a prospective 6-mo iron stable isotope study. Am J Clin Nutr, 2016-08-24;104(4):1030-1038. 2016-08-24 [PMID: 27557657] (Human)
• Wang H, Gottfries J, Barrenas F, Benson M Identification of novel biomarkers in seasonal allergic rhinitis by combining proteomic, multivariate and pathway analysis. PLoS ONE, 2011-08-24;6(8):e23563. 2011-08-24 [PMID: 21887273] (Human)

FAQs for alpha 1-Acid Glycoprotein (DAGP00). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: ORM1