HSD17B6 Antibody [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Applications: ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 647

HSD17B6 Antibody [Alexa Fluor™ Plus 647] Summary

• Immunogen: Produced in rabbits immunized with E. coli-derived Human HSD17B6 fragment.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HSD17B6
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HSD17B6 Antibody [Alexa Fluor™ Plus 647]

• 17-beta-HSD 6
• 17-beta-HSD6
• 17-beta-hydroxysteroid dehydrogenase type 6
• 3(alpha->beta)-hydroxysteroid epimerase
• 3-alpha->beta-HSE
• EC 1.1.1
• EC 1.1.1.105
• EC 1.1.1.62
• EC 1.1.1.63
• HSE3-hydroxysteroid epimerase
• hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)
• hydroxysteroid (17-beta) dehydrogenase 6
• NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
• Oxidative 3-alpha hydroxysteroid dehydrogenase
• oxidative 3-alpha-hydroxysteroid-dehydrogenase
• oxidoreductase
• retinol dehydrogenase
• RODH3(alpha->beta)-hydroxysteroid epimerasel
• SDR9C6
• short chain dehydrogenase/reductase family 9C, member 6,3-alpha->beta-hydroxysteroid epimerase

Background

HSD17B6 is encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HSD17B6