Recombinant Human HRSP12 Protein

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SDS-Page: Recombinant Human HRSP12 Protein [NBP1-50921] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human HRSP12 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-137 of Human HRSP12

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSSLIRRVIS TAKAPGAIGP YSQAVLVDRT IYISGQIGMD PSSGQLVSGG VAEEAKQALK NMGEILKAAG CDFTNVVKTT VLLADINDFN TVNEIYKQYF KSNFPARAAY QVAALPKGSR IEIEAVAIQG PLTTASL

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
HRSP12
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
16.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl, 1mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human HRSP12 Protein

  • EC 3.1
  • heat-responsive protein 12perchloric acid-soluble protein
  • P14.5
  • PSPribonuclease UK114
  • translational inhibitor protein p14.5,14.5 kDa translational inhibitor protein
  • UK114 antigen homolog
  • UK114translational inhibitor p14.5

Background

HRSP12, also called ribonuclease UK114, is an endoribonuclease found predominantly in human adult kidney and liver, and which is responsible for inhibiting translation by cleaving mRNA. This protein cleaves phosphodiester bonds only in single-stranded RNA. It may be an important biomarker for heptatic carcinoma. Recombinant human HRSP12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol HRSP12