HRC Antibody - BSA Free

Immunohistochemistry-Paraffin: HRC Antibody [NBP1-81208] - Analysis in human heart muscle and liver tissues using NBP1-81208 antibody. Corresponding HRC RNA-seq data are presented for the same tissues.

Western Blot: HRC Antibody [NBP1-81208] - Analysis in human heart tissue.

Immunohistochemistry-Paraffin: HRC Antibody [NBP1-81208] - Staining of human heart muscle shows strong cytoplasmic positivity in cardiomyocytes.

Immunohistochemistry-Paraffin: HRC Antibody [NBP1-81208] - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes.

Immunohistochemistry-Paraffin: HRC Antibody [NBP1-81208] - Staining of human duodenum shows no positivity in glandular cells as expected.

Immunohistochemistry-Paraffin: HRC Antibody [NBP1-81208] - Staining of human liver shows no positivity in hepatocytes as expected.

• Reactivity: Hu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HRC Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: SHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HRC
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:1000 - 1:2500
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  HRC Protein (NBP1-81208PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for HRC Antibody - BSA Free

• HCP
• histidine rich calcium binding protein
• MGC133236
• sarcoplasmic reticulum histidine-rich calcium-binding protein

Background

The HRC gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcopl

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HRC Antibody (NBP1-81208)(1)

Publication using NBP1-81208

• Boncompagni S, Thomas M, Lopez JR et al. Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. PLoS One 2012-01-01 [PMID: 22768324]

Bioinformatics

• Gene Symbol: HRC
• Entrez:
  • 3270(Human)