HPRG Antibody (RM0091-9G42)

Product Discontinued

HPRG Antibody (RM0091-9G42) Summary

• Immunogen: Mouse recombinant protein of HPRG
• Specificity: This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant protein of HPRG.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: HRG
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 0.2 um filtered PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Alternate Names for HPRG Antibody (RM0091-9G42)

• DKFZp779H1622
• Histidine-proline-rich glycoprotein
• histidine-rich glycoprotein
• HPRG
• HPRGHRGP
• HRG

Background

HRG (histidine-rich glycoprotein) contains two cystatin-like domains and is located in plasma and platelets. The physiological function is not yet known. It binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin, and the lysine-binding site of plasminogen. A potential prothrombotic effect of HRG is indicated by the inhibition of fibrinolysis and the reduction of inhibition of coagulation. Mutations in HRG lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HRG
• Entrez:
  • 94175(Mouse)
• Uniprot:
  • Q9ESB3(Mouse)