HP1 alpha Antibody

Western Blot: HP1 alpha Antibody [H00023468-B01P] - Analysis of CBX5 expression in IMR-32.

Immunocytochemistry/Immunofluorescence: HP1 alpha Antibody [H00023468-B01P] - Analysis of purified antibody to CBX5 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: HP1 alpha Antibody [H00023468-B01P] - Analysis of CBX5 expression in C32.

Western Blot: HP1 alpha Antibody [H00023468-B01P] - Analysis of CBX5 expression in transfected 293T cell line by CBX5 polyclonal antibody. Lane 1: CBX5 transfected lysate(21.01 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

HP1 alpha Antibody Summary

• Immunogen: CBX5 (NP_036249.1, 1 a.a. - 191 a.a.) full-length human protein. MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKETAKS
• Marker: Heterochromatin Marker
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CBX5
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional, Immunofluorescence

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HP1 alpha Antibody

• Antigen p25
• chromobox homolog 5 (Drosophila HP1 alpha)
• chromobox homolog 5 (HP1 alpha homolog, Drosophila)
• chromobox homolog 5
• chromobox protein homolog 5
• Heterochromatin protein 1 homolog alpha
• heterochromatin protein 1-alpha
• HP1 alpha homolog
• HP1 alpha
• HP1
• HP1A
• HP1-ALPHA
• HP1Hs alpha
• HP1Hs-alpha

Background

Heterochromatin protein-1 (HP1) is a methyl-lysine binding adapter protein that is involved in a variety important functions in the cell nucleus. Localized at heterochromatin sites, HP1 is responsible for gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin.

HP1 antibodies are useful tools for research on transcription regulation and epigenetic signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CBX5
• Uniprot:
  • NP_036249.1(Human)