HO-2/HMOX2 Antibody (322913) [Alexa Fluor™ Plus 405]

• Clone: 322913
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

HO-2/HMOX2 Antibody (322913) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human and mouse HO‑2/HMOX2 in Western blots. Endogenous rat HO-2 is detectable but has a higher background. In Western blots, no cross-reactivity with recombinant human HO-1/HMOX1 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for HO-2/HMOX2 Antibody (322913) [Alexa Fluor™ Plus 405]

• heme oxygenase (decycling) 2
• heme oxygenase 2
• HMOX2
• HO2
• HO-2
• HO-2EC 1.14.99.3

Background

Heme Oxygenase 2 (HO-2), also known as HMOX2, is a 36 kDa microsomal enzyme required for the metabolism of heme to biliverdin. Heme Oxygenase occurs as 2 isozymes, the constitutively expressed Heme Oxygenase-2(HO-2/HMOX2) and the inducible Heme Oxygenase-1 (HO-1/HMOX1). HO-1 expression is induced by heme and other non-heme compounds. Human HO-2 shares 42% amino acid sequence identity with human HO-1 and 89% amino acid sequence identity with mouse and rat HO-2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.