HNF-4 gamma/NR2A2 Antibody

Immunohistochemistry-Paraffin: HNF-4 gamma/NR2A2 Antibody [NLS5160] - Analysis of anti-HNF4G / HNF4 Gamma antibody with human breast, carcinoma.

Immunohistochemistry-Paraffin: HNF-4 gamma/NR2A2 Antibody [NLS5160] - Analysis of anti-HNF4G / HNF4 Gamma antibody with human small intestine.

Product Discontinued

HNF-4 gamma/NR2A2 Antibody Summary

• Immunogen: Synthetic 17 amino acid peptide from ligand-binding domain of human HNF4G.
• Specificity: Human HNF4G. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Mouse (94%), Rat (94%), Hamster (94%), Canine (94%), Opossum (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HNF4G
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Gorilla, Gibbon, Marmoset. Predicted cross-reactivity based on sequence identity: Elephant (94%), Panda (94%), Platypus (94%), Equine (88%), Turkey (88%), Chicken (88%), Lizard (82%), Seabass (82%), Pufferfish (82%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for HNF-4 gamma/NR2A2 Antibody

• hepatocyte nuclear factor 4, gamma
• hepatocyte nuclear factor 4-gamma
• HNF4 gamma
• HNF-4 gamma
• HNF4G
• HNF-4-gamma
• NR2A2
• NR2A2Nuclear receptor subfamily 2 group A member 2
• NR2A3

Background

Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 - 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HNF4G
• Entrez:
  • 3174(Human)
• Uniprot:
  • Q14541(Human)