HNF-3 beta/FoxA2 Antibody (4C2)

Western Blot: HNF-3 beta/FoxA2 Antibody (4C2) [H00003170-M07] - Analysis of FOXA2 expression in human pancreas.

Immunocytochemistry/Immunofluorescence: HNF-3 beta/FoxA2 Antibody (4C2) [H00003170-M07] - Analysis of monoclonal antibody to FOXA2 on HeLa cell. Antibody concentration 10 ug/ml

Immunohistochemistry-Paraffin: HNF-3 beta/FoxA2 Antibody (4C2) [H00003170-M07] - Analysis of monoclonal antibody to FOXA2 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml

ELISA: HNF-3 beta/FoxA2 Antibody (4C2) [H00003170-M07] - Detection limit for recombinant GST tagged FOXA2 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC, IHC-P
• Clone: 4C2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

HNF-3 beta/FoxA2 Antibody (4C2) Summary

• Immunogen: FOXA2 (NP_068556, 363 a.a. ~ 457 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
• Specificity: FOXA2 - forkhead box A2
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FOXA2
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500
• Application Notes: Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HNF-3 beta/FoxA2 Antibody (4C2)

• forkhead box A2
• Forkhead box protein A2
• FoxA2
• hepatic nuclear factor-3-beta
• hepatocyte nuclear factor 3, beta
• hepatocyte nuclear factor 3-beta
• HNF3 beta
• HNF-3 beta
• HNF-3B
• HNF-3-beta
• HNF3BTCF-3B
• MGC19807
• TCF3B
• Transcription factor 3B

Background

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FOXA2
• Entrez:
  • 3170(Human)
• OMIM:
  • 600288(Human)
• Uniprot:
  • NP_068556(Human)