Histone H4 [Trimethyl Lys5] Peptide

Product Discontinued

Histone H4 [Trimethyl Lys5] Peptide Summary

• Description: A Biotinylated peptide corresponding to amino acids 1 - 25 of Histone H4 [Trimethyl Lys5] Peptide.

  Source: Synthetic peptide

  Amino Acid Sequence: MSGRGKGGKGLGKGGAKRHRKVLRD

• Modification: Trimethyl Lys5
• Protein/Peptide Type: Peptide
• Gene: HIST4H4

Applications/Dilutions

• Dilutions:
  • Block/Neutralize
  • Dot Blot
  • ELISA
  • Functional
  • Gel Super Shift Assays
  • Peptide ELISA
  • Radioimmunoassay
• Application Notes: This Histone H3 peptide is useful for Blocking/Neutralizing, Dot Blot, ELISA, Gel Super Shift Assays, Peptide ELISA, Radioimmunoassay, and Functional Assays.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized. Reconstitute in diH20.
• Preservative: No Preservative

Notes

All peptides supplied with nanospray MS , HPLC analysis and CID MS/MS peptide sequence confirmation. Modifications shown on the right side are C-terminal; biotin on the C-terminus is added to the side-chain of lysine (epsilon amine) as Ahx-biotin (Ahx = aminohexanoate).

Alternate Names for Histone H4 [Trimethyl Lys5] Peptide

• H4
• H4/A
• H4/B
• H4/C
• H4/D
• H4/E
• H4/G
• H4/H
• H4/I
• H4/J
• H4/K
• H4/M
• H4/N
• H4/O
• H4/p
• H4F2
• H4FA
• H4FB
• H4FC
• H4FD
• H4FE
• H4FG
• H4FH
• H4FI
• H4FJ
• H4FK
• H4FM
• H4FN
• H4FO
• H4K5Me3
• H4M
• HIST1H4A
• HIST1H4B
• HIST1H4C
• HIST1H4D
• HIST1H4E
• HIST1H4F
• HIST1H4H
• HIST1H4I
• HIST1H4J
• HIST1H4K
• HIST1H4L
• HIST2H4
• HIST2H4A
• HIST2H4B
• HIST4H4
• histone 4, H4
• Histone Cluster 1 H4
• Histone Cluster 1 H4i
• Histone Cluster 4 H4
• histone cluster 4, H4
• Histone H4
• MGC24116

Background

Histone proteins H3, H4, H2A, and H2B function as building blocks to package eukaryotic DNA into repeating nucleosome units that are folded in higher order chromatin fibers. The nucleosome is composed of an octamer containing a H3/H4 tetramer and two H2A/H2B dimers, surrounded by approximately 146 base pairs of DNA. A diverse and elaborate array of post-translational modifications including acetylation, phosphorylation, methylation, ubiquitination, and ADP-ribosylation occurs on the N-terminal tail domains of histones. Methylation of position-specific lysine residues in histone N termini is a central modification for regulating epigenetic transitions in chromatin. Each methylatable lysine residue can exist in a mono, di, or tri methylated state. Arginine resdiues can also by mono or di methylated.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: HIST4H4