Histone H3 [ac Leu56] Antibody (RM179)


Western Blot: Histone H3 [ac Leu56] Antibody (179) [NBP2-61537] - (1) acid extracts of HeLa cells treated with sodium butyrate and (2) recombinant histone H3.3, at 1 ug/mL, showed a band of histone H3 acetylated at ...read more
Immunocytochemistry/ Immunofluorescence: Histone H3 [ac Leu56] Antibody (179) [NBP2-61537] - HeLa cells treated with sodium butyrate, using Acetyl-Histone H3 (Lys56) Rabbit mAb (red). Actin filaments have been labeled ...read more
Immunohistochemistry: Histone H3 [ac Leu56] Antibody (179) [NBP2-61537] - Staining of HepG2 cells using Anti-Acetyl-Histone H3 (Lys56) antibody
ELISA: Histone H3 [ac Leu56] Antibody (179) [NBP2-61537] - No cross reactivity with unmodified Lysine 56 (K56 ctrl), acetylated Lysine 4 (K4ac), Lysine 9 (K9ac), Lysine 14 (K14ac), Lysine 18 (K18ac), Lysine 23 (K23ac), ...read more

Product Details

Reactivity VbSpecies Glossary
Applications WB, DB, ELISA, ICC/IF, IHC
1 mg/ml

Order Details

Histone H3 [ac Leu56] Antibody (RM179) Summary

Additional Information
Recombinant Monoclonal Antibody
An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys56).
ac Leu56
This antibody reacts to Histone H3 acetylated at Lysine 56 (K56ac). No cross reactivity with other acetylated Lysines in histone H3.
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Western Blot 1 ug/mL - 2 ug/mL
  • Dot Blot 0.5 ug/mL-2 ug/mL
  • ELISA 0.5 ug/mL- 1 ug/mL
  • Immunocytochemistry/Immunofluorescence 0.5 ug/mL - 2 ug/mL
  • Immunohistochemistry 1 ug/mL - 10 ug/mL

Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
50% Glycerol/PBS with 1% BSA
0.09% Sodium Azide
1 mg/ml
Protein A purified

Alternate Names for Histone H3 [ac Leu56] Antibody (RM179)

  • H3 histone, family 3A
  • H3.3AH3F3H3F3B
  • H3.3B
  • H3F3A
  • Histone H3
  • histone H3.3
  • MGC87782
  • MGC87783


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Blogs on Histone H3.

Article Review: Glucose-induced transcriptional regulation in cancer
Epigenetic mechanisms have been implicated in many physiological and pathophysiological processes. Among these, histone modifications including methylation, phosphorylation, acetylation and ubiquitination, significantly modify gene expression. In c...  Read full blog post.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...  Read full blog post.

The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...  Read full blog post.

EZH1 has more to offer than gene repression
EZH1 is part of the Polycomb-group family of proteins, which are responsible for remodeling chromatin in genes and modulating epigenetic silencing during development.  Specifically, EZHI is a component of PRC2, or polycomb repressive complex-2.  PR...  Read full blog post.

Understanding Transcription with RNA Polymerase II
RNA polymerase II is a large 12-subunit complex that synthesizes all mRNAs and several non-coding RNAs in eukaryotic cells. It is a DNA-dependent RNA polymerase enzyme that catalyzes transcription of DNA into RNA based on the four ribonucleoside triph...  Read full blog post.

Histone H3
Eukaryotic chromosomes are formed through the highly organized and structural wrapping of DNA genetic material around histone proteins into the classic "bead on a string" globular structure of nucleosomes. The histone family consists of five family me...  Read full blog post.

EZH2: Epigenetic Regulation Made Easy!
Enhancer of Zeste homolog 2 (EZH2) is the methyltransferase enzyme responsible for trimethylating lysine 27 on histone H3 to produce H3K27Me3. EZH2 is a polycomb group protein that is an essential epigenetic regulator that is often found deregulated i...  Read full blog post.

Understanding the Reasons for Histone H3 K4 Trimethylation (H3K4Me3)
Epigenetic mechanisms allow distinction between the active and inactive compartments of the genome, allowing proper cell lineage and embryogenesis. The trimethylation of Histone 3 at lysine 4 (H3K4Me3) is a common epigenetic histone modification that...  Read full blog post.

The 'epi-genie' is Out of the Bottle: Functional Histone 3 Variants in Human Disease
Discovery of histone variants using highly specific antibodies has led to the emerging notion that alterations in histone modifications and further changes in chromatin structure are induced by exchange of histone variants. Covalent histone modificati...  Read full blog post.

"Come Fly with Me" - New Drosophila Model Developed for Direct in Vivo Study of Histones
Forming the major protein component of chromatin, histones are essential to the structure and organization of chromosomes, forming the nucleosome around which DNA is packaged and wrapped.Antibody studies have revealed histones undergo various posttr...  Read full blog post.

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Gene Symbol HIST2H3C