Histone Deacetylase 8/HDAC8 Antibody - C-terminus

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Histone Deacetylase 8/HDAC8 Antibody - C-terminus Summary

Immunogen
A synthetic peptide near the C-terminus of human HDAC8 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC8
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
This antibody has been tested by ELISA and western blot and is useful in Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~41kDa corresponding to the appropriate cell lysate or extract.

Reactivity Notes

BLAST analysis was used to suggest cross-reactivity with rat, mouse, human, and bovine based on 100% sequence homology. Cross-reactivity with HDAC8 from other sources has not been determined.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 30% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Histone Deacetylase 8/HDAC8 Antibody - C-terminus

  • EC 3.5.1.98
  • HD8
  • HDAC8
  • HDACL1
  • Histone Deacetylase 8
  • histone deacetylase-like 1
  • RPD3

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol HDAC8