HIP1 Antibody Pair

Product Discontinued

HIP1 Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00003092-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human HIP1.
  
  
• Capture antibody: rabbit MaxPab affinity purified polyclonal anti-HIP1 (100 ug)
• Detection antibody: mouse purified polyclonal anti-HIP1 (20 ug)
• Standard Curve Range: 0.3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: HIP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 0.3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for HIP1 Antibody Pair

• HIP-1
• HIP-I
• huntingtin interacting protein 1
• huntingtin-interacting protein 1
• Huntingtin-interacting protein I
• ILWEQ
• MGC126506

Background

Huntingtin Interacting Protein (HIP1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin's disease. Huntingtin's is a neurodegenerate disease caused by the expansion of a polymorphic glutamine tract in Huntingtin.

In addition to playing a role in Huntingtin disease, HIP1 is likely to be involved in the recruitment of clathrin coats to lipid membranes, and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: HIP1