Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS Protein

Product Discontinued

Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-199 of Human Hematopoietic Prostaglandin D Synthase/HPGDS
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMPNYKL TYFNMRGRAE IIRYIFAYLD IQYEDHRIEQ ADWPEIKSTL PFGKIPILEV DGLTLHQSLA IARYLTKNTD LAGNTEMEQC HVDAIVDTLD DFMSCFPWAE KKQDVKEQMF NELLTYNAPH LMQDLDTYLG GREWLIGNSV TWADFYWEIC STTLLVFKPD LLDNHPRLVT LRKKVQAIPA VANWIKRRPQ TKL

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: HPGDS
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 25.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.15 M NaCl, 1 mM DTT
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human Hematopoietic Prostaglandin D Synthase/HPGDS Protein

• EC 2.5.1.18
• EC 5.3.99.2
• glutathione S-transferase sigma
• Glutathione S-transferase
• Glutathione-dependent PGD synthase
• Glutathione-requiring prostaglandin D synthase
• GST class-sigma
• GSTS
• GSTShematopoietic prostaglandin D2 synthase
• hematopoietic prostaglandin D synthase
• HPGDS
• H-PGDS
• PGDS
• PGDSglutathione-dependent PGD synthetase
• Prostaglandin-H2 D-isomerase
• PTGDS2

Background

HPGDS, also known as GSTS, is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. Recombinant human HPGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: HPGDS