Hematopoietic Prostaglandin D Synthase/HPGDS Products

Antibodies
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
MAB6487
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
AF6487
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
NBP1-83322
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
NBL1-14330
Applications: WB
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
H00027306-T01
Applications: WB
Proteins
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
NBP1-83322PEP
Species: Hu
Applications: AC
Hematopoietic Prostaglandin D ...
Hematopoietic Prostaglandin D Synt...
NBP1-98970
Species: Hu
Applications: PAGE

Description

Prostaglandin D synthase catalyzes the isomerization of PGH2 to produce PGD2. Prostaglandin D synthase induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin type enzyme (b-trace) and the hematopoietic enzyme. Lipocalin type prostaglandin D synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as b-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic prostaglandin D synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione-S-transferases.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 27306
Alternate Names
  • GST class-sigma
  • Glutathione S-transferase
  • Prostaglandin-H2 D-isomerase
  • PTGDS2
  • Glutathione-requiring prostaglandin D synthase
  • EC 5.3.99.2
  • Glutathione-dependent PGD synthase
  • EC 2.5.1.18
  • H-PGDS
  • GSTShematopoietic prostaglandin D2 synthase
  • PGDSglutathione-dependent PGD synthetase
  • glutathione S-transferase sigma
  • hematopoietic prostaglandin D synthase

Pathways for Hematopoietic Prostaglandin D Synthase/HPGDS

View related products by pathway and learn more about each of the pathways below.

Localization
Inflammatory Response
Acute Inflammatory Response
Cyclooxygenase Pathway
Angiogenesis
Pathogenesis
Conjugation

Bioinformatics Tool for Hematopoietic Prostaglandin D Synthase/HPGDS

Discover related pathways, diseases and genes to Hematopoietic Prostaglandin D Synthase/HPGDS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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