GRB7 Antibody (OTI15E7)

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI15E7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

GRB7 Antibody (OTI15E7) Summary

• Immunogen: Full length human recombinant protein of human GRB7 (NP_005301) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRB7
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-2000

Packaging, Storage & Formulations

• Storage: Store at -20 degrees C. Avoid freeze/thaw cycles.
• Buffer: PBS (pH 7.3) 1% BSA, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: >95%

Alternate Names for GRB7 Antibody (OTI15E7)

• B47
• Epidermal growth factor receptor GRB-7
• GRB7 adapter protein
• GRB7
• growth factor receptor-bound protein 7

Background

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRB7