GRAP2 Antibody (OTI1G2) [Alexa Fluor™ Plus 488]

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, IHC, CyTOF-ready
• Clone: OTI1G2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

GRAP2 Antibody (OTI1G2) [Alexa Fluor™ Plus 488] Summary

• Immunogen: Full length human recombinant protein of human GRAP2(NP_004801) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GRAP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for GRAP2 Antibody (OTI1G2) [Alexa Fluor™ Plus 488]

• Adapter protein GRID
• GADS
• GADSSH3-SH2-SH3 adapter Mona
• GRAP2
• GRB2L
• GRB-2-like protein
• GRB2-related adapter protein 2
• GRB2-related adaptor protein 2
• GRB2-related protein with insert domain
• GRBLG
• GRBLGGRAP-2
• GRBX
• Grf40 adapter protein
• Grf40
• grf-40
• GRID
• GRIDGRPL
• Growth factor receptor-binding protein
• growth factor receptor-bound protein 2-related adaptor protein 2
• GRPL
• Hematopoietic cell-associated adapter protein GrpL
• hematopoietic cell-associated adaptor protein GRPL
• Mona
• P38
• Protein GADS
• SH3-SH2-SH3 adaptor molecule

Background

GRAP2 encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRAP2