gp130/CD130 Antibody Pair [HRP]

Sandwich ELISA: gp130/CD130 Antibody Pair [HRP] [NBP2-79535] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

• Reactivity: Mu
• Applications: ELISA
• Conjugate: HRP
• Standard Curve Range: 11.72-750 pg/ml (example only; lot dependent)
• Sensitivity: 11.72 pg/ml (example only; lot dependent)

gp130/CD130 Antibody Pair [HRP] Summary

• Description: Solid Phase sandwich ELISA for the quantitative determination of Mouse gp130/CD130.
• Additional Information: Recombinant Monoclonal Antibody
• Specificity: This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Mouse gp130/CD130.
• Source: HEK293
• Standard Curve Range: 11.72-750 pg/ml (example only; lot dependent)
• Sensitivity: 11.72 pg/ml (example only; lot dependent)
• Assay Type: Sandwich ELISA
• Sample Volume: 100 ul
• Gene: IL6ST

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for gp130/CD130 Antibody Pair [HRP]

• CD130 antigen
• CD130
• CDw130
• DKFZp564F053
• gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form
• gp130
• IL-6 receptor subunit beta
• IL-6R subunit beta
• IL-6RB
• IL-6R-beta
• IL6ST
• interleukin 6 signal transducer (gp130, oncostatin M receptor)
• interleukin receptor beta chain
• interleukin-6 receptor subunit beta
• Interleukin-6 signal transducer
• Membrane glycoprotein 130
• membrane glycoprotein gp130
• Oncostatin-M receptor subunit alpha

Background

CD130 is encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: IL6ST