GM2A Antibody

Western Blot: GM2A Antibody [H00002760-B01P] - Analysis of GM2A expression in transfected 293T cell line by GM2A polyclonal antibody. Lane 1: GM2A transfected lysate(21.34 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

GM2A Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GM2A (AAH09273, 1 a.a. - 193 a.a.) full-length human protein. MQSLMQAPLLIALGLLLAAPAQAHLKKPSQLSSFSWDNCDEGKDPAVIRSLTLEPDPIVVPGNVTLSVVGSTSVPLSSPLKVDLVLEKEVAGLWIKIPCTDYIGSCTFERFCDVLDMLIPTGEPCPEPLRTYGLPCHCPFKEGTYSLPKSEFVVPDLELPSWLTTGNYRIESVLSSSGKRLGCIKIAASLKGI
• Specificity: GM2A - GM2 ganglioside activator,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: GM2A
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GM2A Antibody

• Cerebroside sulfate activator protein
• ganglioside GM2 activator
• GM2 ganglioside activator
• GM2-AP
• SAP-3GM2 ganglioside activator protein
• Shingolipid activator protein 3
• sphingolipid activator protein 3

Background

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GM2A
• Entrez:
  • 2760(Human)
• Uniprot:
  • AAH09273(Human)