GM2A Products

Antibodies
GM2A Antibody
GM2A Antibody
NBP1-87090
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GM2A Antibody
GM2A Antibody
NBP1-72046
Species: Hu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
GM2A Antibody
GM2A Antibody
NBP1-72045
Species: Hu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
GM2A Overexpression Lysate (D ...
GM2A Overexpression Lysate (Denatu...
H00002760-T01
Species: Hu
Applications: WB
GM2A Overexpression Lysate (N ...
GM2A Overexpression Lysate (Native)
NBL1-11135
Applications: WB
Proteins
GM2A Recombinant Protein
GM2A Recombinant Protein
H00002760-P01
Species: Hu
Applications: WB, ELISA, PA
GM2A Partial Recombinant Prot ...
GM2A Partial Recombinant Protein
H00002760-Q01
Species: Hu
Applications: WB, ELISA, PA
GM2A Recombinant Protein Anti ...
GM2A Recombinant Protein Antigen
NBP1-87090PEP
Species: Hu
Applications: AC
RNAi
GM2A RNAi
GM2A RNAi
H00002760-R01
Species: Hu

Description

GM2A, also known as Ganglioside GM2 activator, is a 193 amino acid that is 21 kDa, with lysosome subcellular location, acts as s a lipid transfer protein that stimulates the enzymatic processing of gangliosides and T-cell activation; acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A which, together with this activator, catalyzes the degradation of the ganglioside GM2; also displays some calcium-independent phospholipase activity. Disease research on this protein has shown a relationship with tay-sachs disease, gangliosidosis, gangliosidosis gm2, sandhoff disease, neurological disorder, candidiasis, protein s deficiency, neurodegenerative disease, tay-sachs disease ab variant, spinal muscular atrophy, lysosomal storage disease, muscular atrophy, sinusitis, gastric cancer, cholesterol, and neuronitis. The GM2A protein has also shown an interaction with PLD2, GPLD1 and HEXA in the Sphingolipid metabolism, glycosphingolipid metabolism, lysosome, and phospholipid metabolism pathways.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2760
Alternate Names
  • sphingolipid activator protein 3
  • Shingolipid activator protein 3
  • ganglioside GM2 activator
  • Cerebroside sulfate activator protein
  • SAP-3GM2 ganglioside activator protein
  • GM2-AP
  • GM2 ganglioside activator

PTMs for GM2A

Learn more about PTMs related to GM2A.

Hydroxylation

Bioinformatics Tool for GM2A

Discover related pathways, diseases and genes to GM2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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