Glycophorin C Antibody (BRIC10) - BSA Free

• Reactivity: Hu
• Applications: WB, Flow
• Clone: BRIC10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

Glycophorin C Antibody (BRIC10) - BSA Free Summary

• Description: Novus Biologicals Mouse Glycophorin C Antibody (BRIC10) - BSA Free (NB100-66522) is a monoclonal antibody validated for use in WB and Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human erythrocytes
• Specificity: NB100-66522 recognizes an epitope in the N-terminal region of CD236, also known as glycophorin C (GPC). CD236 is an integral membrane protein which carries the Gerbich blood group antigens. Expression of CD236 is not restricted to erythroid cells, but is broadly distributed in both erythroid and non-erythroid tissues.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GYPC
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Tris-Glycine (pH 7.4)
• Preservative: 0.01% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein G purified

Alternate Names for Glycophorin C Antibody (BRIC10) - BSA Free

• CD236 antigen
• CD236
• CD236R
• GE
• GLPC
• glycoconnectin
• glycophorin C (Gerbich blood group)
• glycophorin-C
• glycophorin-D
• Glycoprotein beta
• GPCMGC126191
• GPD
• GYPD
• MGC117309
• MGC126192
• PAS-2
• PAS-2'
• Sialoglycoprotein D

Background

CD236 is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. CD236 (Glycophorin C) plays an important role in regulating the stability of red cells. Expression of Glycophorin C is not restricted to erythroid cells but is broadly distributed in both erythroid and non erythroid tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Glycophorin C Antibody (NB100-66522)(1)

Publication using NB100-66522

• Docherty CK, Nilsen M, Loughlin L. 2-Methoxyestradiol Attenuates Hypoxia-Induced Pulmonary Hypertension Via Alterations in Hypoxia Inducible Factor a ATS

Bioinformatics

• Gene Symbol: GYPC
• Entrez:
  • 2995(Human)
• Uniprot:
  • P04921(Human)