Glutathione S-transferase Mu 5 Antibody

Images

 
Western Blot: Glutathione S-transferase Mu 5 Antibody [NBP1-32682] - Sample (50 ug of whole cell lysate) A: rat testis 12% SDS PAGE; antibody diluted at 1:10000.
Immunocytochemistry/ Immunofluorescence: Glutathione S-transferase Mu 5 Antibody [NBP1-32682] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Glutathione S-transferase Mu 5 Antibody [NBP1-32682] - Paraffin-embedded SG xenograft, using antibody at 1:500 dilution.
Western Blot: Glutathione S-transferase Mu 5 Antibody [NBP1-32682] - (30 ug of whole cell lysate) A: H1299 12% SDS PAGE diluted at 1:1000
Western Blot: Glutathione S-transferase Mu 5 Antibody [NBP1-32682] - Sample (50 ug of whole cell lysate) A: mouse testis 12% SDS PAGE; antibody diluted at 1:10000.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Glutathione S-transferase Mu 5 Antibody Summary

Immunogen
Full length human GSTM5 Recombinant protein.
Localization
Cytoplasm
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GSTM5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:5000-1:20000

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for Glutathione S-transferase Mu 5 Antibody

  • EC 2.5.1.18
  • glutathione S-alkyltransferase M5
  • glutathione S-aralkyltransferase M5
  • glutathione S-aryltransferase M5
  • glutathione S-transferase M5
  • glutathione S-transferase mu 5
  • GST class-mu 5
  • GSTM5-5
  • GTM5
  • S-(hydroxyalkyl)glutathione lyase M5

Background

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GSTM5