Glutathione Peroxidase 2/GPX2 Antibody

Product Discontinued

Glutathione Peroxidase 2/GPX2 Antibody Summary

• Immunogen: Synthetic peptide C-NIEPDIKRLLKVAI, representing the C-Terminus of the human protein sequence according to NP_002074.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GPX2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA 1:64000
• Application Notes: This antibody can be used for ELISA and Western Blot. In Western Blot, approx 22kDa band observed in Mouse Colon tissue extracts at 1/1000 dilution. Not tested in other applications. Not tested in other applications. Recommended Starting Dilution:* ELISA (peptide): 1:4,000 WB: * *Optimal dilutions should be determined by the end user.
• Control:

  Glutathione Peroxidase 2/GPX2 Overexpression Lysate

Reactivity Notes

Tested: Mouse. Expected from sequence similarity: Human, Mouse

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Glutathione Peroxidase 2/GPX2 Antibody

• EC 1.11.1
• EC 1.11.1.9
• gastrointestinal glutathione peroxidase 2
• Gastrointestinal glutathione peroxidase
• GIGPX
• GI-GPx
• glutathione peroxidase 2 (gastrointestinal)
• Glutathione Peroxidase 2
• Glutathione peroxidase-gastrointestinal
• Glutathione peroxidase-related protein 2
• GPRP
• GPRP-2
• GPX2
• GPx-2
• GPx-GI
• GSHPx-2
• GSHPX-GI

Background

This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPX2
• Entrez:
  • 2877(Human)
  • 14776(Mouse)
• Uniprot:
  • NP_002074.(Human)