Glucose Transporter GLUT6 Antibody (OTI7E3) [Janelia Fluor® 646]

Product Discontinued

Glucose Transporter GLUT6 Antibody (OTI7E3) [Janelia Fluor® 646] Summary

• Immunogen: Full-length protein expressed in 293T cell transfected with human Glucose Transporter GLUT6 expression vector.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLC2A6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Glucose Transporter GLUT6 Antibody (OTI7E3) [Janelia Fluor® 646]

• Glucose transporter type 6
• Glucose transporter type 9
• GLUT6
• GLUT-9
• GLUT9GLUT-6
• HSA011372
• solute carrier family 2 (facilitated glucose transporter), member 6
• solute carrier family 2, facilitated glucose transporter member 6

Background

Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. Seven types of glucose transport carrier proteins, designated as Glut 1 to 7, facilitate glucose transport across the cell membrane. Molecular cloning of glucose transporters have identified a family of closely related genes that encode at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers. The majority of differences in sequence homology in Glut proteins occur at 4 hydrophilic domains that may play a role in distinct tissue specific pattern of expression and targeting. All Glut proteins are glycosylated at or near the C terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes as in blood brain barrier and blood testis barriers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLC2A6